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April 12, 2017Journal of Medical Case ReportsOpen Access

A 50-year-old man with primary adrenal diffuse large B-cell lymphoma achieved a complete metabolic response following left adrenalectomy and six cycles of CHOP chemotherapy.

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Population

1 50-year-old Pakistani man with primary left adrenal diffuse large B-cell lymphoma and a 21-year history of…

Design

Case_report

Key result

A 50-year-old man with primary adrenal diffuse large B-cell lymphoma achieved a complete metabolic response following left adrenalectomy and six cycles of CHOP chemotherapy.

Authors

NRNanik RamOROwais RashidSFSaad Farooq

Discussion

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Member takes

Overview

May support adrenalectomy plus CHOP in primary adrenal DLBCL; leaves open need for prospective validation.

Study Design

Type

Case Report (n=1)

Multicenter

No

Structured PICO

P
Population
A 50-year-old man with primary left adrenal diffuse large B-cell lymphoma who underwent adrenalectomy and CHOP chemotherapy.
I
Intervention
Left adrenalectomy followed by 6 cycles of CHOP chemotherapy (cyclophosphamide, doxorubicin, vincristine, and prednisone).
O
Outcome
Clinical and metabolic response to treatment.

Primary adrenal diffuse large B-cell lymphoma can be successfully treated with adrenalectomy and CHOP chemotherapy, achieving complete metabolic response even without rituximab.

Limitations

  • Optimal treatment protocol has not yet been established
  • Single case report limits generalizability

Cite This Study

Ram et al. (2017) conducted a case report in Primary adrenal non-Hodgkin lymphoma (n=1). Left adrenalectomy and CHOP chemotherapy was evaluated on Metabolic response. A 50-year-old man with primary adrenal diffuse large B-cell lymphoma achieved a complete metabolic response following left adrenalectomy and six cycles of CHOP chemotherapy.

synapsesocial.com/papers/6a6f236a75498292b708884ahttps://doi.org/10.1186/s13256-017-1271-x
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Confirmation of the molecular classification of diffuse large B-cell lymphoma by immunohistochemistry using a tissue microarray2003 · 4,324 citations
  2. 2Adrenal lymphoma: presentation, management and prognosis2016 · 73 citations
  3. 3PET–CT of Extranodal Lymphoma2004 · 79 citations
  4. 4Prognostic factors in primary diffuse large B-cell lymphoma of adrenal gland treated with rituximab-CHOP chemotherapy from the Consortium for Improving Survival of Lymphoma (CISL)2012 · 98 citations