Key result
Inoculation of specific-pathogen-free chickens and turkeys with parvoviruses resulted in productive virus replication only in the homologous host species.
The VP1 gene plays an essential role in host specificity of chicken and turkey parvoviruses and could be a relevant target sequence for strain classification.
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VP1 may guide species-specific diagnostics for avian parvoviruses; leaves open its role in field strain classification.
Inoculation of specific-pathogen-free chickens and turkeys with five chicken parvoviruses (ChPV) and five turkey parvoviruses (TuPV) resulted in productive virus replication only in the homologous host species. A phylogenetic tree based on nucleotide sequences of the VP1 gene segment revealed a host-specific clustering of the virus strains. These results suggest that the VP1 gene plays an essential role in host specificity of ChPV and TuPV strains and could be a relevant target sequence for strain classification.Nota de Investigación- Especificidad de hospedador y relaciones filogenéticas de parvovirus de pollos y pavos.La inoculación de pollos y pavos libres de patógenos específicos con cinco parvovirus de pollo (ChPV) y cinco parvovirus de pavo (TuPV) dio lugar a la replicación viral productiva únicamente en la especie hospedadora homóloga. El árbol filogenético basado en las secuencias de nucleótidos del segmento del gene VP1 reveló una agrupación de las cepas virales específica de hospedador. Estos resultados sugieren que el gene VP1 juega un papel esencial en la especificidad del hospedador de las cepas de parvovirus de pollo y de pavo y podría ser una secuencia blanco relevante para la clasificación de las cepas.
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Zsak et al. (2015) studied Parvovirus infection. Inoculation with chicken and turkey parvoviruses vs. Heterologous host species was evaluated on Productive virus replication and phylogenetic clustering. Inoculation of specific-pathogen-free chickens and turkeys with parvoviruses resulted in productive virus replication only in the homologous host species.
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