Key result
Regular physical activity and endurance training improve cardiovascular health by altering vascular cell gene expression and increasing vascular shear stress.
Why the study?
Does regular physical activity (endurance training) improve vascular health through changes in gene expression and mechanosensory mechanisms?
Does regular physical activity (endurance training) improve vascular health through changes in gene expression and mechanosensory mechanisms?
This review highlights the molecular and mechanosensory mechanisms, particularly increased shear stress and altered gene expression, by which endurance training improves vascular health.
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Extends mechanistic links between exercise and vascular health; leaves open optimal shear stress thresholds for clinical translation.
Whyte et al. (2010) conducted a review in Cardiovascular health. Regular physical activity (endurance training) was evaluated. Regular physical activity and endurance training improve cardiovascular health by altering vascular cell gene expression and increasing vascular shear stress.
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