Answers are grounded in this paper and cite their sources.
Demonstrates an efficient synthesis of triazoles in various conditions, suggesting broad applicability.
A metal‐free domino reaction was developed for efficient synthesis of 4,5‐disubstituted 1,2,3‐( NH )‐triazoles by sequentially coupling sulfur salts with aldehydes and sodium azide. In the presence of L ‐proline, olefinic sulfur salt intermediates rather than epoxides are formed in situ via the coupling of sulfur salts with aldehydes and cyclize with azide ion. This process features mild conditions, high efficiency, commercially available starting materials, and wide substrate scope. magnified image
No takes yet. Share an insight, caveat, or question.
Wu et al. (2018) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: