Key result
Intraoperative cerebral oximetry monitoring-guided intervention significantly reduced the incidence of postoperative delirium compared to control (11.9% vs 23.8%, OR 0.28).
Why the study?
Whether intraoperative cerebral oximetry monitoring-guided intervention reduces the risk of postoperative cognitive dysfunction remains controversial.
Does intraoperative cerebral oximetry monitoring-guided intervention reduce postoperative delirium in adult patients undergoing cardiac surgery?
Meta-Analysis (n=1,868)
Does intraoperative cerebral oximetry monitoring-guided intervention reduce postoperative delirium in adult patients undergoing cardiac surgery?
Odds Ratio: 0.28 (95% CI 0.09–0.84)
Absolute Event Rate: 11.9% vs 23.8%
p-value: p=0.02
Intraoperative cerebral oximetry monitoring-guided intervention is associated with a lower risk of postoperative delirium and cognitive decline, and shorter ICU stay in adults undergoing cardiac surgery.
No takes yet. Share an insight, caveat, or question.
rSO2-guided intervention shows no clear benefit for postoperative cognition after cardiac surgery; leaves open need for standardized large RCTs.
Tian et al. (2022) conducted a meta-analysis in Cardiac surgery (n=1,868). Intraoperative cerebral oximetry monitoring-guided intervention vs. Control was evaluated on Postoperative delirium (POD) (OR 0.28, 95% CI 0.09-0.84, p=0.02). Intraoperative cerebral oximetry monitoring-guided intervention significantly reduced the incidence of postoperative delirium compared to control (11.9% vs 23.8%, OR 0.28).
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