Key result
EEG-guided anesthesia cuts postoperative delirium ~25%, while rSO2 monitoring reduces cognitive decline.
Why the study?
It remained controversial whether the use of intraoperative cerebral function monitoring can decrease the incidence of perioperative neurocognitive disorders.
Does intraoperative cerebral function monitoring (EEG and rSO2) reduce perioperative neurocognitive disorders in surgical patients?
Meta-Analysis (n=6,356)
Does intraoperative cerebral function monitoring (EEG and rSO2) reduce perioperative neurocognitive disorders in surgical patients?
Odds Ratio: 0.75 (95% CI 0.6–0.93)
p-value: p=0.008
Intraoperative use of EEG and/or rSO2 monitoring can decrease the risk of perioperative neurocognitive disorders, including postoperative delirium and cognitive decline.
No takes yet. Share an insight, caveat, or question.
Supports EEG/rSO2 monitoring in non-cardiac surgery to lower POD/POCD risk; reinforces meta-analytic evidence from RCTs.
Ding et al. (2020) conducted a meta-analysis in Perioperative neurocognitive disorders (PND) (n=6,356). Electroencephalography (EEG) and regional cerebral oxygen saturation (rSO2) monitoring vs. Routine care (without EEG or rSO2 monitoring) was evaluated on Incidence of postoperative delirium (POD) with EEG-guided anesthesia (OR 0.75, 95% CI 0.60-0.93, p=0.008). Intraoperative EEG-guided anesthesia reduced the risk of postoperative delirium (OR 0.75), and regional cerebral oxygen saturation monitoring reduced postoperative cognitive decline (OR 0.53).
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