Key result
Severe preoperative resting pain increased the risk of postoperative delirium (OR 3.7; 95% CI 1.5-9.0), while using oral opioids instead of IV PCA decreased the risk (OR 0.4; 95% CI 0.2-0.7).
Why the study?
Are postoperative pain and pain management strategies associated with postoperative delirium in elderly patients undergoing major noncardiac surgery?
Cohort (n=333)
Are postoperative pain and pain management strategies associated with postoperative delirium in elderly patients undergoing major noncardiac surgery?
Odds Ratio: 0.4 (95% CI 0.2–0.7)
Preoperative pain and the method of postoperative pain management are significant independent predictors of postoperative delirium in elderly patients undergoing major noncardiac surgery.
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May link postoperative pain to delirium risk in elderly surgical patients; hypothesis-generating and requires prospective confirmation.
Vaurio et al. (2006) conducted a cohort in Postoperative delirium (n=333). Oral opioid analgesics vs. Opioid analgesics via IV patient-controlled analgesia was evaluated on Development of postoperative delirium (OR 0.4, 95% CI 0.2-0.7). Severe preoperative resting pain increased the risk of postoperative delirium (OR 3.7; 95% CI 1.5-9.0), while using oral opioids instead of IV PCA decreased the risk (OR 0.4; 95% CI 0.2-0.7).
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