The effect of early postoperative acute pain on postoperative delirium in older persons undergoing abdominal surgery: a secondary analysis of multicenter prospective data

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Discussion

Secondary analysis shows that early pain increases the risk of postoperative delirium in older persons, suggesting better pain management is needed.

Delirium occurred in 13.2% of the cohort, with higher rates in those experiencing moderate-to-severe pain.
Univariate and multivariate logistic regression identified a significant association between early pain and delirium outcomes.
Analysis involved a secondary data review from multicenter hospitals across China, focusing on older surgical patients.
Evidence highlights the need for improved analgesic strategies to reduce the risk of delirium in older patients.

Lv et al. (2025) studied this question.

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Secondary analysis shows that early pain increases the risk of postoperative delirium in older persons, suggesting better pain management is needed.