In a healthy Korean population, females had significantly lower (better) left ventricular global longitudinal systolic strain compared to males (-21.2% vs. -19.5%, p < 0.001).
Cross-Sectional (n=501)
Yes
This study establishes normal reference values for 2-dimensional left ventricular strain and strain rate in a healthy Korean population, highlighting significant sex-based differences.
Absolute Event Rate: -21.2% vs -19.5%
p-value: p=< 0.001
Echocardiographic images were acquired and measured at each institute according to a standard method outlined by the American Society of Echocardiography. 15) All conventional echocardiographic parameters were measured and averaged Background: It is important to understand the distribution of 2-dimensional strain values in normal population. We performed a multicenter trial to measure normal echocardiographic values in the Korean population. Methods: This was a substudy of the Normal echOcardiogRaphic Measurements in KoreAn popuLation (NORMAL) study. Echocardiographic specialists measured frequently used echocardiographic indices in healthy people according to a standardized method at 23 different university hospitals. The strain values were analyzed from digitally stored images. Results: Of a total of 1003 healthy participants in NORMAL study, 2-dimensional strain values were measured in 501 subjects (265 females, mean age 47 15 years old) with echocardiographic images only by GE echocardiographic machines. Interventricular septal thickness, left ventricular (LV) posterior wall thickness, systolic and diastolic LV dimensions, and LV ejection fraction were 7.5 1.0 mm, 7.4 1.0 mm, 29.9 2.8 mm, 48.9 3.6 mm, and 62 4%, respectively. LV longitudinal systolic strain (LS) values of apical 4-chamber (A4C) view, apical 3-chamber (A3C) view, apical 2-chamber (A2C) view, and LV global LS (LVGLS) were -20.1 2.3, -19.9 2.7, -21.2 2.6, and -20.4 2.2%, respectively. LV longitudinal systolic strain rate (LVLSR) values of the A4C view, A3C view, A2C view, and LV global LSR (LVGLSR) were -1.18 0.18, -1.20 0.21, -1.25 0.21, and -1.21 0.21 -s , respectively. Females had lower LVGLS (-21.2 2.2% vs. -19.5 1.9%, p < 0.001) and LVGLSR (-1.25 0.18 -s vs. -1.17 0.15 -s , p < 0.001) values than males.
Park et al. (Fri,) conducted a cross-sectional in Healthy adults (n=501). Female sex vs. Male sex was evaluated on Left ventricular global longitudinal systolic strain (LVGLS) (p=< 0.001). In a healthy Korean population, females had significantly lower (better) left ventricular global longitudinal systolic strain compared to males (-21.2% vs. -19.5%, p < 0.001).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: