Normal Range of Left Ventricular 2-Dimensional Strain
Key result
Left ventricular 2-D strain measurements differed significantly among three ultrasound vendors, demonstrating low inter-vendor agreement and indicating that strain data are not interchangeable.
Why the study?
What is the normal range of left ventricular 2-dimensional strain and are there vendor-specific differences?
Population
817 healthy subjects, age range 0-88 years
Comparison
2-D speckle tracking analysis using ultrasound… vs Comparison among the 3 vendors
Design
Cross-sectional
Authors
Discussion
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Member takes
Implication
LV strain values require consistent vendor use for serial monitoring; leaves open standardization of reference ranges.
Study Design
Type
Cross-Sectional (n=817)
Multicenter
Yes
Structured PICO
What is the normal range of left ventricular 2-dimensional strain and are there vendor-specific differences?
P
Population
817 healthy subjects, age range 0-88 years
I
Intervention
2-D speckle tracking analysis using ultrasound systems from 3 different vendors
C
Comparator
Comparison among the 3 vendors
O
Outcome
Normal range of LV 2-D strain (radial, circumferential, longitudinal) and inter-vendor variabilitysurrogate
Normal 2-D strain values vary significantly by ultrasound vendor, indicating that strain data are not interchangeable across different vendors for longitudinal or cross-sectional assessments.
Cite This Study
Takigiku et al. (2012) conducted a cross-sectional in Healthy (n=817). 2-D speckle tracking echocardiography vs. Three different ultrasound vendors was evaluated on Global radial, circumferential, and longitudinal strain. Left ventricular 2-D strain measurements differed significantly among three ultrasound vendors, demonstrating low inter-vendor agreement and indicating that strain data are not interchangeable.