Key result
The hypertension/arthritis multimorbidity pattern was associated with greater physical function decline, and developing new conditions most impacted decline in those with a cardiometabolic pattern.
Why the study?
Studies had not simultaneously examined the impact of multimorbidity patterns and disease accumulation on functional decline.
Do distinct multimorbidity patterns and the subsequent accumulation of conditions predict longitudinal trajectories of physical function decline in older adults?
Population
6 634 participants aged at least 60 years from China
Comparison
Different multimorbidity patterns and subsequently developed conditions
Design
Population-based cohort study
Follow-up
across 4 waves
Authors
Loading...
May warrant monitoring older adults with hypertension/arthritis multimorbidity; extends multimorbidity research but leaves causal effects open.
Cohort (n=6,634)
Yes
Do distinct multimorbidity patterns and the subsequent accumulation of conditions predict longitudinal trajectories of physical function decline in older adults?
Different multimorbidity patterns have distinct impacts on baseline physical function and its longitudinal decline, highlighting the need to consider both the combination and progressive nature of chronic conditions to identify older adults at risk of disability.
Liu et al. (2021) conducted a cohort in Multimorbidity (n=6,634). Multimorbidity patterns vs. Other multimorbidity patterns was evaluated on Changes in physical function. The hypertension/arthritis multimorbidity pattern was associated with greater physical function decline, and developing new conditions most impacted decline in those with a cardiometabolic pattern.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: