Demonstrates effective treatment for infectious keratitis in a patient with keratoprosthesis, suggesting a new surgical approach.
Purpose: To describe the use of Rose Bengal Photodynamic Antimicrobial Therapy (RB-PDAT) combined with amniotic membrane graft (AMG) as a novel surgical technique for infectious keratitis in a patient with Boston Keratoprosthesis (B-Kpro) type 1 Lucia. Methods: A 91-year-old woman with a history of B-Kpro type 1 Lucia implantation in both eyes presented for routine follow-up complaining of pain and redness in the left eye. Slit-lamp examination revealed a 6 mm corneal infiltrate with an epithelial defect adjacent to the optic stem. After 2 weeks of topical antimicrobial therapy without any improvement, the decision was made to perform RB-PDAT in conjunction with an AMG. The infectious keratitis resolved within 21 days. Conclusions: The combination of RB-PDAT and AMG may be considered as a surgical alternative in patients with keratoprosthesis complicated by severe infectious keratitis refractory to standard medical treatment.
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Eskenazi-Betech et al. (2025) studied this question.
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