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This research investigates the relationship between leukocyte telomere length and human life span, specifically in adults.

February 26, 2020JAMA Network OpenOpen Access

Association of Leukocyte Telomere Length With Mortality Among Adult Participants in 3 Longitudinal Studies

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This research investigates the relationship between leukocyte telomere length and human life span, specifically in adults.
Cohort study involving 3,259 adults of European ancestry from CHS, FHS, and WHI.
Leukocyte telomere length was measured at multiple time points between 1992 and 1998.
Data analysis was conducted from February 2017 to December 2019.
Shorter leukocyte telomere length was linked to a higher risk of all-cause mortality (HR 1.34, 95% CI 1.21-1.47).
For noncancer causes of death, a 1-kilobase decrease in telomere length increased cardiovascular death risk (HR 1.28, 95% CI 1.08-1.52).
The effect was strongest for other or unknown causes of death (HR 1.53, 95% CI 1.32-1.77).

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Cohort study examines the link between leukocyte telomere length and mortality in adults, suggesting implications for understanding life span limits.

Arbeev et al. (2020) studied this question.

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Cohort study examines the link between leukocyte telomere length and mortality in adults, suggesting implications for understanding life span limits.