Key result
The age-adjusted incidence of acute myocardial infarction increased significantly in men from 42.7 to 50.1 per 100,000 person-years over 15 years, driven particularly by younger men with accumulating metabolic syndrome risk factors.
Population
6,222 patients with a first-ever AMI and 2,400 age-matched controls from the Yamagata AMI Registry in Japan.
Design
Cohort
Follow-up
1993 to 2007
Authors
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Rising AMI rates in younger Japanese adults may warrant earlier risk screening; leaves open causal role of dyslipidemia in observational data.
Observational (n=6,222)
Yes
Absolute Event Rate: 50.1% vs 42.7%
p-value: p=0.0099
Nishiyama et al. (2010) conducted an observational in Acute Myocardial Infarction (n=6,222). Time period (2003-2007 vs 1993-1997) and coronary risk factors vs. Earlier time periods and age-matched general population controls was evaluated on Age-adjusted incidence of AMI in men (per 100,000 person-years) (p=0.0099). The age-adjusted incidence of acute myocardial infarction increased significantly in men from 42.7 to 50.1 per 100,000 person-years over 15 years, driven particularly by younger men with accumulating metabolic syndrome risk factors.
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