Key result
Renal denervation led to blood pressure control on 2 antihypertensive agents and normalization of left ventricular structure and function within 1 year in an obese patient with resistant hypertension.
Why the study?
Does renal denervation improve blood pressure control and left ventricular function in an obese patient with resistant hypertension and heart failure?
Case Report (n=1)
Does renal denervation improve blood pressure control and left ventricular function in an obese patient with resistant hypertension and heart failure?
Renal denervation, along with weight reduction, can successfully control resistant hypertension and reverse hypertension-mediated organ damage such as left ventricular dysfunction.
Hypothesis-generating for renal denervation in resistant hypertension with HF; larger trials needed before practice change.
We described the diagnostic workup and management of an obese patient with resistant hypertension, who was hospitalized for heart failure. The case was complicated by comorbidities such as diabetes mellitus. After the exclusion of pseudohypertension, renal denervation was the final treatment option. Within 1 year, the procedure led to control of blood pressure on just 2 antihypertensive agents and to normalization of the structure and function of the left ventricle. Reduction of the body mass index also contributed to maintaining a healthy condition of up to 6 years after the surgical procedure.
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Zhang et al. (2019) conducted a case report in Resistant hypertension (n=1). Renal denervation was evaluated on Blood pressure control and normalization of left ventricular structure and function. Renal denervation led to blood pressure control on 2 antihypertensive agents and normalization of left ventricular structure and function within 1 year in an obese patient with resistant hypertension.
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