Key result
Induction of ≥2 atrial tachycardias during ablation was associated with worse acute success compared to induction of a single atrial tachycardia (77% vs 100%, P=0.009).
Why the study?
Atrial tachycardia is common in adult congenital heart disease and challenging to map and ablate, prompting investigation into whether substrate characteristics relate to ablation outcomes using ultra-high-density mapping.
Does the induction of multiple atrial tachycardias and larger low voltage areas predict worse ablation outcomes in adults with congenital heart disease?
Population
Adults with congenital heart disease undergoing 23 procedures with 50 ATs mapped
Comparison
1 single AT induced (group A) vs >=2 ATs induced (group B)
Design
Observational cohort study
Follow-up
Up to 12 months
Authors
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May refine risk stratification for ACHD ablation; hypothesis-generating and requires prospective validation before guiding practice.
Observational (n=23)
Does the induction of multiple atrial tachycardias and larger low voltage areas predict worse ablation outcomes in adults with congenital heart disease?
Absolute Event Rate: 77% vs 100%
p-value: p=0.009
In adults with congenital heart disease, larger atrial low voltage areas are associated with multiple inducible atrial tachycardias, longer procedure times, and worse acute and midterm ablation outcomes.
Mantziari et al. (2019) conducted an observational in Atrial tachycardia in adults with congenital heart disease (n=23). Induction of ≥2 atrial tachycardias (Group B) vs. Induction of 1 single atrial tachycardia (Group A) was evaluated on Acute success (p=0.009). Induction of ≥2 atrial tachycardias during ablation was associated with worse acute success compared to induction of a single atrial tachycardia (77% vs 100%, P=0.009).
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