Key result
Cardiovascular differentiation in embryonic stem cells is strictly regulated by specific signaling molecules, hypoxia, and developmentally controlled gene expression.
Understanding the molecular and structural events of cardiovascular differentiation in embryonic stem cells is crucial for directing these cells to specific lineages for therapeutic use.
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Advances in vitro modeling of vertebrate cardiogenesis; leaves open translation to clinical regenerative therapies.
Sauer et al. (2004) conducted a review in Cardiovascular development. Cardiovascular differentiation in embryonic stem cells is strictly regulated by specific signaling molecules, hypoxia, and developmentally controlled gene expression.
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