Key result
The in vivo enthalpy of hydrolysis of phosphorylcreatine during isometric contraction of frog muscle is approximately 10.6 kcal/mole, consistent across twitches and tetani.
Population
iodoacetate-poisoned frogs' sartorii muscles at 0 degrees C
Design
Preclinical
Authors
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Provides baseline muscle energetics data; leaves open translation to mammalian cardiac bioenergetics.
Effect estimate: 10.6 kcal/mole
This basic science study establishes that the in vivo enthalpy of hydrolysis of phosphorylcreatine in frog muscle is approximately 10.6 kcal/mole.
Carlson et al. (1967) studied Frog muscle physiology. Isometric contraction was evaluated on In vivo enthalpy of hydrolysis of phosphorylcreatine (10.6 kcal/mole). The in vivo enthalpy of hydrolysis of phosphorylcreatine during isometric contraction of frog muscle is approximately 10.6 kcal/mole, consistent across twitches and tetani.
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