Key result
Evaluation of 30 children with hand, foot, and mouth disease in Atlanta identified intracytoplasmic inclusions in vesicular scrapings and evidence of asymptomatic infection in contacts.
Observational (n=30)
No
This report describes an outbreak of hand, foot, and mouth disease in Atlanta, highlighting clinical features, diagnostic challenges, and novel cytological findings.
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Recognizes hand-foot-mouth syndrome in US children; extends early international reports of coxsackie A16 and leaves open questions on transmission.
James E. Froeschle (1967) conducted an observational in Hand, Foot, and Mouth Disease (Coxsackievirus A16 infection) (n=30). Coxsackievirus A16 infection was evaluated on Clinical, virologic, serologic, epidemiologic features, and cytological studies. Evaluation of 30 children with hand, foot, and mouth disease in Atlanta identified intracytoplasmic inclusions in vesicular scrapings and evidence of asymptomatic infection in contacts.
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