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December 1, 1991Diabetes

Gestational diabetes mellitus was associated with a significantly higher rate of cesarean delivery compared to matched controls (35.3% vs. 22%, P<0.01).

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Why the study?

Do women with gestational diabetes mellitus have higher rates of obstetric complications compared to matched controls?

Population

150 women with gestational diabetes mellitus and 305 control subjects matched for age, parity, and ethnicity.

Comparison

Intensive diet therapy and self-monitoring of… vs Control subjects matched for age, parity, and…

Design

Cohort

Key result

Gestational diabetes mellitus was associated with a significantly higher rate of cesarean delivery compared to matched controls (35.3% vs. 22%, P<0.01).

Authors

MGMindy GoldmanJKJohn L. KitzmillerBABarbara Abrams

Discussion

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Member takes

Overview

Elevated cesarean rates in gestational diabetes warrant attention; leaves open whether management reduces this risk.

Study Design

Type

Case-Control (n=455)

Structured PICO

Do women with gestational diabetes mellitus have higher rates of obstetric complications compared to matched controls?

P
Population
455 women, including 150 with gestational diabetes mellitus and 305 matched controls, assessed retrospectively for obstetric complications.
E
Exposure
Intensive diet therapy and self-monitoring of capillary blood glucose to obtain postprandial euglycemia (22% required insulin).
C
Comparator
Control subjects matched for age, parity, and ethnicity.
O
Outcome
Obstetric complications including polyhydramnios, preterm labor, pyelonephritis, hypertension, preeclampsia, abnormalities of labor, birth trauma, fetal macrosomia, and cesarean delivery.hard clinical

Main Result

Absolute Event Rate: 35.3% vs 22%

p-value: p=<0.01

Women with gestational diabetes mellitus have higher rates of cesarean delivery and hypertensive complications compared to matched controls, despite intensive management.

Cite This Study

Goldman et al. (1991) conducted a case-control in Gestational diabetes mellitus (n=455). Gestational diabetes mellitus vs. Matched control subjects without gestational diabetes mellitus was evaluated on Cesarean delivery (p=<0.01). Gestational diabetes mellitus was associated with a significantly higher rate of cesarean delivery compared to matched controls (35.3% vs. 22%, P<0.01).

synapsesocial.com/papers/6a62dd5d809dd4a9e2c1a5afhttps://doi.org/10.2337/diab.40.2.s79
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Examination of gestational diabetes mellitus at a tertiary care hospital2024 · 1 citations
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  3. 3Maternal Weight Gain in Women Who Develop Gestational Diabetes Mellitus2012 · 143 citations
  4. 4Non-obese gestational diabetes: A unique risk profile for maternal and fetal outcomes2025
  5. 5Gestational Outcomes Related to the Occurrence of Gestational Diabetes Mellitus: A Cohort Study2024 · 1 citations