Key result
Higher triglyceride levels were associated with reduced odds of ischemic stroke (OR 0.94; 95% CI 0.88-0.99), whereas total cholesterol was significantly elevated in stroke patients.
Why the study?
Changes in lipid profile have been reported as a risk factor for ischemic stroke, but further evaluation was needed on lipid profile levels and their association with acute ischemic stroke within the first 24 hours.
Are lipid profile levels associated with acute ischemic stroke?
Population
48 acute ischemic stroke patients aged above 35 years and 48 controls
Comparison
Acute ischemic stroke patients vs controls
Design
Cross-sectional analytical study
Authors
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Lipid profile changes may associate with acute ischemic stroke within 24 hours; hypothesis-generating in cross-sectional data, needing prospective confirmation.
Cross-Sectional (n=96)
No
Are lipid profile levels associated with acute ischemic stroke?
Odds Ratio: 0.94 (95% CI 0.88–0.99)
Increased total cholesterol is a risk factor for ischemic stroke, whereas higher triglyceride levels were paradoxically associated with a protective role against ischemic stroke events in this cohort.
Bhattacharyya et al. (2024) conducted a cross-sectional in Ischemic stroke (n=96). Lipid profile levels vs. Controls was evaluated on Ischemic stroke (OR 0.94, 95% CI 0.88-0.99). Higher triglyceride levels were associated with reduced odds of ischemic stroke (OR 0.94; 95% CI 0.88-0.99), whereas total cholesterol was significantly elevated in stroke patients.
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