Key result
Increasing age and male gender were associated with significant differences in postural cardiac autonomic modulation, including higher low-frequency power in men compared to women (supine P<0.001).
Why the study?
Do gender and aging affect differential autonomic responses to orthostatic maneuvers in volunteers?
Population
362 volunteers (206 females, age range: 10-88 years)
Comparison
Orthostatic maneuver vs Supine position and comparisons across gender…
Design
Cross-sectional
Authors
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Gender and age differences in postural autonomic responses remain incompletely defined; larger studies needed to clarify mechanisms and relevance.
Observational (n=362)
Do gender and aging affect differential autonomic responses to orthostatic maneuvers in volunteers?
p-value: p=<0.001
Postural cardiac autonomic modulation differs significantly between men and women and declines with normal aging, which may explain differences in orthostatic tolerance.
Barantke et al. (2008) conducted an observational in Healthy volunteers (n=362). Aging and male gender vs. Younger age and female gender was evaluated on Spontaneous baroreflex sensitivity (BRS) and heart rate variability parameters (LF, HF, TP) during postural change (p=<0.001). Increasing age and male gender were associated with significant differences in postural cardiac autonomic modulation, including higher low-frequency power in men compared to women (supine P<0.001).
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