Key result
Standing for 10 minutes increased mean blood pressure from 96 to 106 mmHg in elderly subjects, whereas young subjects maintained blood pressure with a larger heart rate increase (27 vs 7 beats/min).
Why the study?
How do circulatory adjustments to standing differ between healthy young and elderly subjects?
Population
60 healthy subjects, comprising 20 young and 40 elderly.
Comparison
Standing for up to 10 minutes. vs Comparison between young and elderly subjects.
Design
Cross-sectional
Follow-up
10 minutes
Authors
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No age-specific initial standing precautions indicated in healthy elderly; leaves open relevance to frail or symptomatic patients.
Observational (n=60)
How do circulatory adjustments to standing differ between healthy young and elderly subjects?
Elderly subjects rely on progressive increases in total peripheral resistance to maintain blood pressure during prolonged standing, whereas young subjects rely more on heart rate increases.
Wieling et al. (1992) conducted an observational in Healthy (n=60). Standing vs. Young subjects was evaluated on Continuous responses of blood pressure, heart rate, stroke volume, and total peripheral resistance to standing. Standing for 10 minutes increased mean blood pressure from 96 to 106 mmHg in elderly subjects, whereas young subjects maintained blood pressure with a larger heart rate increase (27 vs 7 beats/min).
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