Key result
Urine microalbumin levels >20 mg/L were significantly associated with the presence of coronary artery disease (abnormal Gensini score) with an odds ratio of 21 compared to normal levels.
Why the study?
Does the degree of urine microalbuminuria correlate with the severity of coronary artery disease assessed by Gensini score?
Cross-Sectional (n=233)
No
Does the degree of urine microalbuminuria correlate with the severity of coronary artery disease assessed by Gensini score?
Microalbuminuria shows a significant positive correlation with the severity of coronary artery disease as measured by the Gensini score.
Answers are grounded in this paper and cite their sources.
Microalbuminuria may refine CAD severity assessment pre-angiography; leaves open incremental prognostic value beyond established risks.
Background: Microalbuminuria is one of the simple and independent risk factor for Coronary artery disease. The study was aimed to study the severity of Coronary artery disease with degree of Microalbuminuria using Gensini scoring. Methodology: Our study consisted of 233 subjects admitted for coronary angiography .All subjects were asked detailed medical history mainly concentrating on important risk factors like Diabetes, Hypertension and physical examination was thoroughly carried out; detection of urine Microalbumin and Coronary angiography was carried on. Gensini scoring was used to assess the severity of CAD. Results: Out of 233 subjects which were studied, 140 were diabetics (60.1%). 95% of Diabetics had abnormal Gensini score, which is statistically significant (p=0.004<0.01), 84% of Non diabetic subjects had abnormal Gensini score (suggests CAD), with odds ratio 3.6 (CI 1.4 to 9.3). Diabetics had a mean age of 60years and Non Diabetics is 58years in our study. There was good correlation between Microalbuminuria and Gensini score with r= +0.510 (p=0.0001) and also good correlation between Diabetes duration and Gensini score with r= +0.626 (p=0.0001). Conclusion: Severity of CAD as assessed by Gensini score was higher in patients with higher microalbuminuria.
No takes yet. Share an insight, caveat, or question.
VH et al. (2015) conducted a cross-sectional in Coronary Artery Disease (n=233). Microalbuminuria (>20 mg/L) vs. Normal urine albumin (<20 mg/L) was evaluated on Abnormal Gensini score (indicating coronary artery disease) (OR 21, 95% CI 2.748-157.485, p=<0.001). Urine microalbumin levels >20 mg/L were significantly associated with the presence of coronary artery disease (abnormal Gensini score) with an odds ratio of 21 compared to normal levels.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: