Why the study?
What is the prevalence of microalbuminuria and its associated risk factors in non-diabetic patients with coronary artery disease?
What is the prevalence of microalbuminuria and its associated risk factors in non-diabetic patients with coronary artery disease?
Microalbuminuria is highly prevalent (88.3%) in non-diabetic patients with coronary artery disease, particularly among smokers, suggesting its potential utility in risk stratification.
High microalbuminuria prevalence in non-diabetic CAD, especially smokers, should not yet change practice; longitudinal studies needed to confirm prognostic value.
The present study was an observational cross sectional study which included sixty non diabetic subjects of both sexes with coronary artery disease admitted as inpatients in Meenakshi Medical College Hospital & Research Institute in Kanchipuram during the study period between February 2014 – September 2015. Majority of subjects were in the age group 51 to 60 yrs (40%), followed by > 60 years (30%), 41 to 50 years (20%) and < 40 years (10%). Age distribution suggests that CAD is more common after 50 years. The results showed that 66.7% of CAD subjects had positive family history of CAD; Prevalence of Microalbuminuria among CAD patients without diabetes was 88.3%; Smokers are at 10.74 time higher risk for microalbuminuria than Nonsmokers, and this observation was highly statistically significant CAD subjects with HDL <40 in Females and < 50 in males are at 2.042 times higher risk for Microalbuminuria than subjects with Normal HDL levels, but risk was not statistically significant. It is concluded that this study recommends estimating Urinary Albumin excretion for 24 hours to identify high risk individuals for Coronary Artery Disease and to add this laboratory workup as a tool for Primary Prevention of CAD.
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Pradhep et al. (2017) studied this question.
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