Key result
Prednisone treatment led to the complete resolution of malaise, lymphadenopathy, and eosinophilia in a patient with Kimura disease, with no recurrence during 18 months of follow-up.
Case Report (n=1)
No
Highlights a rare case of Kimura disease presenting with severe eosinophilia and multiple lymphadenopathy, diagnosed via lymph node excision.
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May prompt inclusion of Kimura disease in eosinophilia-lymphadenopathy differentials; leaves open optimal diagnostic and therapeutic strategies.
Kimura disease is a benign rare chronic inflammatory disorder of unknown aetiology. This disease is mainly endemic in Asia, although cases have also been reported in Europe and America. We describe a case in a 34-year-old Chinese man presenting with severe eosinophilia and multiple lymphadenopathy. Since our initial aim was to rule out the diagnosis of lymphoma, and given the limitations of our laboratory, we decided to perform an excision of one of the cervical lymph nodes. The histological diagnosis was consistent with Kimura disease. We review the epidemiology, the aetiology and clinical features of this entity.
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Carretero et al. (2016) conducted a case report in Kimura disease (n=1). Prednisone was evaluated on Clinical improvement and resolution of symptoms. Prednisone treatment led to the complete resolution of malaise, lymphadenopathy, and eosinophilia in a patient with Kimura disease, with no recurrence during 18 months of follow-up.
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