What is the clinical evidence from this study?

Study design: Case Report. Population: Acute type A aortic dissection in pregnancy with Marfan syndrome (n=1). Intervention: Cesarean delivery, uterine artery embolization, and emergency ascending aortic replacement. Primary outcome: Maternal and fetal survival and hospital discharge.

What does this research mean for the field?

Acute type A aortic dissection can occur in pregnant patients with Marfan syndrome despite only moderate aortic root enlargement, and can be successfully managed through rapid, coordinated multidisciplinary intervention. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To highlight the occurrence and management of acute type A aortic dissection in a pregnant patient with Marfan syndrome.

July 24, 2026Journal of Cardiothoracic SurgeryOpen Access

Emergency ascending aortic replacement for acute type a aortic dissection in a 31-week pregnant patient with Marfan syndrome

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Key result

Combined C-section, embolization, and aortic replacement saves pregnant Marfan patient and newborn following acute dissection.

Why the study?

Acute type A aortic dissection during pregnancy is a rare, life-threatening condition, with increased risk from pregnancy-related hemodynamic changes and genetic conditions like Marfan syndrome.

Population

A 41-year-old pregnant woman at 31 weeks of gestation with Marfan syndrome and type A aortic dissection

Design

Case report

Follow-up

Postoperative day 20

Authors

KUKrišjānis UpenieksRiga Stradiņš University KMKristiāns MeidropsPauls Stradiņš Clinical University Hospital IBIvars BrečsPauls Stradiņš Clinical University Hospital

Discussion

Member takes

Implication

Case report of successful late-pregnancy repair leaves open optimal management strategies; larger series required before practice guidance.

Key Points

To highlight the occurrence and management of acute type A aortic dissection in a pregnant patient with Marfan syndrome.
Presented a case of a 41-year-old woman at 31 weeks of pregnancy with acute chest pain.
Utilized transthoracic echocardiography and computed tomography for diagnosis.
Performed cesarean section followed by emergency ascending aortic replacement.
The patient and newborn were discharged successfully on postoperative day 20.
Aortic dissection occurred despite moderate aortic root enlargement, underlining monitoring needs.
Coordinated multidisciplinary management proved effective in this complex case.

Study Design

Type

Case Report (n=1)

Multicenter

Structured PICO

Population

A 41-year-old pregnant woman at 31 weeks of gestation with Marfan syndrome who presented with acute type A aortic dissection and was managed with a multidisciplinary surgical approach.

Intervention

Multidisciplinary management consisting of cesarean section, prophylactic bilateral uterine artery embolization, and emergency supracoronary ascending aortic replacement using a 28-mm straight graft.

Outcome

Maternal and fetal survival and successful hospital dischargehard clinical

Acute type A aortic dissection in a pregnant patient with Marfan syndrome can be successfully managed with a coordinated approach involving cesarean delivery, uterine artery embolization, and emergency ascending aortic replacement.

Limitations

Single case report limits generalizability

Cite This Study

Upenieks et al. (2026) conducted a case report in Acute type A aortic dissection in pregnancy with Marfan syndrome (n=1). Cesarean delivery, uterine artery embolization, and emergency ascending aortic replacement was evaluated on Maternal and fetal survival and hospital discharge. A multidisciplinary approach combining cesarean delivery, uterine artery embolization, and emergency ascending aortic replacement successfully treated a 31-week pregnant patient with Marfan syndrome and acute type A aortic dissection, allowing discharge of mother and newborn on postoperative day 20.

synapsesocial.com/papers/6a6303c3395161722cd16dc2 https://doi.org/10.1186/s13019-026-04575-y

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July 24, 2026Journal of Cardiothoracic SurgeryOpen Access

Emergency ascending aortic replacement for acute type a aortic dissection in a 31-week pregnant patient with Marfan syndrome

View Full Paper

Ask AI

Bookmark

Key result

Combined C-section, embolization, and aortic replacement saves pregnant Marfan patient and newborn following acute dissection.

Why the study?

Acute type A aortic dissection during pregnancy is a rare, life-threatening condition, with increased risk from pregnancy-related hemodynamic changes and genetic conditions like Marfan syndrome.

Population

A 41-year-old pregnant woman at 31 weeks of gestation with Marfan syndrome and type A aortic dissection

Design

Case report

Follow-up

Postoperative day 20

Authors

KUKrišjānis UpenieksRiga Stradiņš University KMKristiāns MeidropsPauls Stradiņš Clinical University Hospital IBIvars BrečsPauls Stradiņš Clinical University Hospital

Discussion

Member takes

Implication

Case report of successful late-pregnancy repair leaves open optimal management strategies; larger series required before practice guidance.

Key Points

To highlight the occurrence and management of acute type A aortic dissection in a pregnant patient with Marfan syndrome.
Presented a case of a 41-year-old woman at 31 weeks of pregnancy with acute chest pain.
Utilized transthoracic echocardiography and computed tomography for diagnosis.
Performed cesarean section followed by emergency ascending aortic replacement.
The patient and newborn were discharged successfully on postoperative day 20.
Aortic dissection occurred despite moderate aortic root enlargement, underlining monitoring needs.
Coordinated multidisciplinary management proved effective in this complex case.

Study Design

Type

Case Report (n=1)

Multicenter

Structured PICO

Population

A 41-year-old pregnant woman at 31 weeks of gestation with Marfan syndrome who presented with acute type A aortic dissection and was managed with a multidisciplinary surgical approach.

Intervention

Multidisciplinary management consisting of cesarean section, prophylactic bilateral uterine artery embolization, and emergency supracoronary ascending aortic replacement using a 28-mm straight graft.

Outcome

Maternal and fetal survival and successful hospital dischargehard clinical

Limitations

Single case report limits generalizability

Cite This Study

synapsesocial.com/papers/6a6303c3395161722cd16dc2 https://doi.org/10.1186/s13019-026-04575-y

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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