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June 5, 2005European Journal of Cardio-Thoracic SurgeryOpen Access

Surgery for acute type A aortic dissection in pregnant patients with Marfan syndrome

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Key result

Operative aortic repair with concomitant or prior delivery resulted in survival for 3 pregnant patients with Marfan syndrome and acute type A aortic dissection, whereas 1 with fetus in situ died.

Why the study?

What are the outcomes of surgical repair for acute type A aortic dissection in pregnant patients with Marfan syndrome?

Population

4 pregnant patients with Marfan syndrome and acute type A aortic dissection

Design

Case_series

Authors

MSMasayuki SakaguchiHKHiroto KitaharaTSTatsuichiro Seto

Discussion

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Member takes

Overview

May support delivery before or with repair for maternal survival in this setting; hypothesis-generating given small case series.

Study Design

Type

Observational (n=4)

Multicenter

No

Structured PICO

What are the outcomes of surgical repair for acute type A aortic dissection in pregnant patients with Marfan syndrome?

P
Population
4 pregnant patients with Marfan syndrome and acute type A aortic dissection treated at a single institution between 1991 and 2003.
E
Exposure
Surgical aortic repair (combined with cesarean section, following spontaneous delivery, or with fetus in situ)
O
Outcome
Maternal and fetal survival and clinical outcomeshard clinical

Cesarean section with concomitant aortic repair is advocated for pregnant patients with Marfan syndrome and acute type A aortic dissection to optimize maternal and fetal survival.

Cite This Study

Sakaguchi et al. (2005) conducted an observational in Acute type A aortic dissection during pregnancy in Marfan syndrome (n=4). Operative aortic repair was evaluated. Operative aortic repair with concomitant or prior delivery resulted in survival for 3 pregnant patients with Marfan syndrome and acute type A aortic dissection, whereas 1 with fetus in situ died.

synapsesocial.com/papers/6a98bf51dea2d226f518e313https://doi.org/10.1016/j.ejcts.2005.02.047
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Redo surgery for a type A aortic dissection in a pregnant woman with Marfan syndrome: a complex clinical case2021 · 2 citations
  2. 2Surgical Treatment for Acute Type A Aortic Dissection in Pregnancy2000 · 19 citations
  3. 3Emergency ascending aortic replacement for acute type a aortic dissection in a 31-week pregnant patient with Marfan syndrome2026
  4. 4Two Surgical Cases of Acute Aortic Dissection in Pregnancy with Marfan Syndrome2007 · 21 citations
  5. 5Bentall Procedure to Repair Acute Type a Aortic Dissection in Pregnant Marfan Syndrome Woman With Preservation of Pregnancy2023 · 1 citations