What is the clinical evidence from this study?

Study design: Case Report. Population: Acute aortic type A dissection during pregnancy with Marfan syndrome (n=2). Intervention: Emergency aortic root replacement under deep hypothermia. Primary outcome: Postoperative course and fetal outcome.

What question did this study set out to answer?

To describe the surgical management and maternal-fetal outcomes in pregnant women with Marfan syndrome presenting with acute type A aortic dissection.

October 1, 2007Asian Cardiovascular and Thoracic Annals

Two Surgical Cases of Acute Aortic Dissection in Pregnancy with Marfan Syndrome

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Key result

Emergency aortic root replacement under deep hypothermia in two pregnant women with Marfan syndrome and acute aortic dissection resulted in fair postoperative courses, with one intrauterine fetal death.

Population

2 women with Marfan syndrome who experienced acute aortic type A dissection during pregnancy or immediately…

Design

Case_series

Authors

HWHidetaka WakiyamaKagawa Prefectural Central Hospital MNMichihiro NasuToyooka Hospital HFHiroshi FujiwaraNagoya University Hospital

Discussion

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Implication

May save mothers with Marfan syndrome and acute dissection in pregnancy; leaves open optimal fetal protection strategies.

Key Points

To describe the surgical management and maternal-fetal outcomes in pregnant women with Marfan syndrome presenting with acute type A aortic dissection.
Clinical evaluation of two cases of acute aortic type A dissection in women with Marfan syndrome (N=2).
Both patients underwent emergency aortic root replacement under deep hypothermia, one at 21 weeks gestation and the other one day postpartum.
Both maternal patients demonstrated fair postoperative recovery following emergency surgical repair.
Intrauterine fetal death occurred in the patient managed at 21 weeks gestation, while the postpartum patient had already delivered a viable neonate prior to intervention.

Study Design

Type

Case Report (n=2)

Structured PICO

Population

2 pregnant women with Marfan syndrome who experienced acute aortic type A dissection and underwent emergency aortic root replacement.

Intervention

Emergency aortic root replacement under deep hypothermia

Outcome

Maternal postoperative course and fetal outcomehard clinical

Emergency aortic root replacement for acute type A dissection in pregnant women with Marfan syndrome can be life-saving for the mother but carries a significant risk of fetal mortality.

Cite This Study

Wakiyama et al. (2007) conducted a case report in Acute aortic type A dissection during pregnancy with Marfan syndrome (n=2). Emergency aortic root replacement under deep hypothermia was evaluated on Postoperative course and fetal outcome. Emergency aortic root replacement under deep hypothermia in two pregnant women with Marfan syndrome and acute aortic dissection resulted in fair postoperative courses, with one intrauterine fetal death.

synapsesocial.com/papers/6a98bf51dea2d226f518e312 https://doi.org/10.1177/021849230701500527

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Two Surgical Cases of Acute Aortic Dissection in Pregnancy with Marfan Syndrome

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

Two Surgical Cases of Acute Aortic Dissection in Pregnancy with Marfan Syndrome

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

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