Key result
Traditional medicine use (AOR 9.13), being overweight (AOR 3.35), and nonadherence to medication (AOR 2.01) were strongly associated with uncontrolled blood pressure in adult hypertensive patients.
Why the study?
Uncontrolled blood pressure is a significant public health problem associated with high mortality and morbidity, affecting 48% of hypertensive patients in Ethiopia.
What are the determinants of uncontrolled blood pressure among adult hypertensive patients in Southern Ethiopia?
Case-Control (n=384)
Yes
What are the determinants of uncontrolled blood pressure among adult hypertensive patients in Southern Ethiopia?
Odds Ratio: 9.13 (95% CI 5.31–15.69)
Absolute Event Rate: 72.66% vs 19.53%
p-value: p=<0.01
Modifiable factors including traditional medicine use, overweight, poor knowledge, and non-adherence to medication and lifestyle modifications are significant determinants of uncontrolled blood pressure in Ethiopian patients.
Nonadherence to medication was associated with uncontrolled BP; hypothesis-generating for adherence interventions, requires prospective confirmation before practice change.
BACKGROUND: Uncontrolled blood pressure is a significant public health problem associated with a high rate of mortality and morbidity worldwide. In Ethiopia, 48% of hypertensive patients have Uncontrolled blood pressure. Therefore, this study aimed to identify the determinants of uncontrolled blood pressure among adult hypertensive patients on follow-up at the Negele and Adola General Hospitals in the Guji Zone, Oromia, Ethiopia. METHODS: A facility-based, unmatched case-control study was conducted in Negelle and Adola General Hospitals, Guji Zone, from January-01-30, 2023, on 384 samples. Study participants were selected consecutively as they came for treatment until the required sample size was obtained. The data were collected using an interview-administered structured questionnaire and medical chart review. The data were entered into Epi-data version 3.1 and exported to SPSS version 25 for analysis. Binary logistic regression analysis was used to model the association between the dependent and independent variables. The candidate variables with p < 0.25 in the bivariate analysis were entered into the multivariable logistic regression. An Adjusted Odds ratio (AOR) and 95% CI were used to measure the strength of the association. Finally, at p < 0.05, statistical significance was declared. RESULTS: A sample of 384 respondents (128 cases and 256 controls) were included, for a response rate of 100%. No adherence to medication (AOR = 2.01, 95% CI = 1.16-3.44), no adherence to smoking abstinence (AOR = 1.84, 95% CI = 1.05-3.22), no adherence to weight management (AOR = 2.02, 95% CI = 1.04-3.92), poor hypertension knowledge (AOR = 2.18, 95% CI = 1.26-3.76), use of traditional medicine (AOR = 9.13, 95% CI = 5.31-15.69), and overweight (AOR = 3.35, 95% CI = 1.79-6.26) were significantly associated with uncontrolled blood pressure. CONCLUSION: This study revealed that no adherence to medication, smoking, weight management, poor hypertension knowledge, traditional medicine use, and being overweight were determinants of uncontrolled blood pressure. Since these are modifiable and preventable factors, there is a need to implement interventions that will enhance self-care practices in this population to improve treatment outcomes.
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Habtegiorgis et al. (2024) conducted a case-control in Uncontrolled blood pressure (n=384). Traditional medicine use vs. No traditional medicine use was evaluated on Uncontrolled blood pressure (AOR 9.13, 95% CI 5.31-15.69, p=<0.01). Traditional medicine use (AOR 9.13), being overweight (AOR 3.35), and nonadherence to medication (AOR 2.01) were strongly associated with uncontrolled blood pressure in adult hypertensive patients.
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