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Hold them or fold them: The morphology of aggregated amyloid-β depends on the concentration of Cu2+ ions, as shown in the TEM images. Distinct differences in the coordination of Cu2+ ions to amyloid-β are observed by electron spin resonance as the metal concentration increases. The results suggest a correlation between specific Cu2+ ion coordination and the overall morphology of aggregates.
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Jun et al. (2007) studied this question.
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