Key result
The use of a nonfenestrated Cardioform Septal Occluder successfully closed a giant mitral paravalvular leak, improving heart failure symptoms from NYHA class IV to II and normalizing hemolytic anemia.
Why the study?
Fenestrated vascular plugs used for paravalvular leaks often leave incomplete closure and refractory hemolysis, motivating the use of nonfenestrated occluders.
Is the use of a nonfenestrated Cardioform Septal Occluder feasible for the closure of a giant mitral paravalvular leak?
Case Report (n=1)
No
Is the use of a nonfenestrated Cardioform Septal Occluder feasible for the closure of a giant mitral paravalvular leak?
A nonfenestrated Cardioform Septal Occluder may offer a feasible alternative to fenestrated plugs for closing giant mitral paravalvular leaks, potentially addressing issues of incomplete closure and hemolysis.
Hypothesis-generating for nonfenestrated occluder in giant mitral PVL; prospective studies needed before adoption.
A variety of fenestrated vascular plugs have been used to seal paravalvular leaks with meaningful success; however, incomplete closure and refractory hemolysis remains a common problem. We describe the feasibility and rationale of their first experience using a nonfenestrated Cardioform Septal Occluder (Gore Medical, Flagstaff, Arizona) to treat a giant mitral paravalvular leak. (Level of Difficulty: Advanced.)
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Cubeddu et al. (2020) conducted a case report in Giant mitral paravalvular leak (n=1). Nonfenestrated Cardioform Septal Occluder was evaluated on Closure of paravalvular leak and clinical improvement. The use of a nonfenestrated Cardioform Septal Occluder successfully closed a giant mitral paravalvular leak, improving heart failure symptoms from NYHA class IV to II and normalizing hemolytic anemia.
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