Key result
Tachycardia induced by atrial or ventricular pacing caused a proportional decrease in left ventricular ejection time (p<0.001) but did not modify the pre-ejection period or isometric contraction time.
Why the study?
Does atrial or ventricular pacing-induced tachycardia modify systolic time intervals in normal subjects?
Observational (n=21)
No
Does atrial or ventricular pacing-induced tachycardia modify systolic time intervals in normal subjects?
Effect estimate: r=-0.76 (atrial pacing) and r=-0.75 (ventricular pacing)
p-value: p=<0.001
Left ventricular ejection time (LVET) must be corrected for heart rate changes, whereas pre-ejection period (PEP) and isometric contraction time (ICT) do not require correction.
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LVET requires heart-rate correction in tachycardia; PEP and ICT do not, leaving applicability to diseased hearts open.
Ferro et al. (1980) conducted an observational in Healthy (n=21). Atrial or ventricular pacing vs. Resting baseline was evaluated on Relationship between left ventricular ejection time (LVET) and heart rate (r=-0.76 (atrial pacing) and r=-0.75 (ventricular pacing), p=<0.001). Tachycardia induced by atrial or ventricular pacing caused a proportional decrease in left ventricular ejection time (p<0.001) but did not modify the pre-ejection period or isometric contraction time.