Key result
Higher body mass index was more strongly associated with uncontrolled hypertension in men (OR up to 8.58; 95% CI 5.74-12.83) than in women (OR up to 3.63).
Why the study?
Gender-related differences in fat distribution may affect BP control, prompting this assessment of how body mass, BMI, and waist circumference influence the effectiveness of antihypertensive therapy in men and women.
Does higher BMI and waist circumference increase the risk of uncontrolled hypertension differently in Caucasian men compared to women?
Observational (n=12,289)
Does higher BMI and waist circumference increase the risk of uncontrolled hypertension differently in Caucasian men compared to women?
Odds Ratio: 8.58 (95% CI 5.74–12.83)
Obesity and visceral obesity are stronger risk factors for uncontrolled hypertension in men than in women, suggesting a need for sex-specific and weight-adjusted antihypertensive dosing.
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Anthropometric factors may differentially influence BP control by gender in treated hypertensives; leaves open whether they modify therapy response.
Chudek et al. (2021) conducted an observational in Hypertension (n=12,289). Body mass index and waist circumference vs. Lower body mass index and waist circumference was evaluated on Uncontrolled hypertension (OR 8.58, 95% CI 5.74-12.83). Higher body mass index was more strongly associated with uncontrolled hypertension in men (OR up to 8.58; 95% CI 5.74-12.83) than in women (OR up to 3.63).
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