Key result
External wrapping of the ascending aorta significantly reduced aortic cross-clamp time (55.75 vs 79.0 minutes) and cardiopulmonary bypass time compared to the Wheat procedure, with comparable safety and efficacy.
Why the study?
To evaluate the safety and efficacy of a modified extravascular technique for treating mild to moderately dilated ascending aorta in patients with bicuspid aortic valve aortopathy.
Does AVR with ascending aorta wrapping improve perioperative safety and efficacy compared to AVR with ascending aorta replacement in patients with BAV and mild to moderately dilated ascending aorta?
Cohort (n=119)
No
Does AVR with ascending aorta wrapping improve perioperative safety and efficacy compared to AVR with ascending aorta replacement in patients with BAV and mild to moderately dilated ascending aorta?
Absolute Event Rate: 55.75% vs 79%
p-value: p=<0.001
External wrapping of the ascending aorta during AVR in BAV patients with mild to moderate dilatation reduces operative times and early drainage compared to aortic replacement, with similar 12-month outcomes.
BACKGROUND: Evaluate the safety and efficacy of our modified technique of the extravascular procedure for treating mild to moderately dilated ascending aorta in patients with bicuspid aortic valve (BAV) aortopathy. METHODS: From January 2015 to December 2018,119 consecutive patients with BAV and ascending aorta dilatation (dimension 40 mm~ 45 mm) were diagnosed in our institution. Among these,49 patients received aggressive aortic valve replace (AVR) + ascending aorta wrapped (wrapped group) while the other 70 patients received AVR + ascending aorta replacement (wheat group). All patients clinical and follow up data were collected for 12 months. RESULTS: Aortic clamping and cardio-pulmonary bypass times were significantly longer in wheat group than wrap group (P < 0.001and 0.021,respectively). The first 24 h drainage in wheat group were much more than wrap group(P = 0.04). Ascending aorta diameter、left ventricular end diameter and ejection fraction were statistically different between pre- and post-operation (p < 0.001) in both groups, but the heart function and complication were no difference during follow up. CONCLUSIONS: External wrapping of the ascending aorta and wheat procedure have good short-term and long-term results in BAV patients with a mild to moderately dilated ascending aorta. The perioperative period results of external wrapping of the ascending aorta for BAV patients were encouraging.
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Zhu et al. (2020) conducted a cohort in Bicuspid aortic valve (BAV) aortopathy with mild to moderately dilated ascending aorta (n=119). Extravascular wrapping of the ascending aorta with a vascular graft (AVR + Wrap) vs. Ascending aorta replacement (Wheat operation) was evaluated on Aortic cross-clamp (ACC) time in minutes (p=<0.001). External wrapping of the ascending aorta significantly reduced aortic cross-clamp time (55.75 vs 79.0 minutes) and cardiopulmonary bypass time compared to the Wheat procedure, with comparable safety and efficacy.
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