Key result
Wrapping of the ascending aorta during aortic valve replacement resulted in a comparable 5-year survival rate (78.1% vs. 87.5%, p=0.50) and quality of life compared to graft replacement.
Why the study?
Does wrapping of the ascending aorta compared to graft replacement yield comparable clinical outcomes and quality of life in patients with dilated ascending aorta undergoing aortic valve replacement?
Cohort (n=40)
No
Does wrapping of the ascending aorta compared to graft replacement yield comparable clinical outcomes and quality of life in patients with dilated ascending aorta undergoing aortic valve replacement?
Absolute Event Rate: 78.1% vs 87.5%
p-value: p=0.50
Wrapping of the ascending aorta during aortic valve replacement yields comparable long-term survival and quality of life to graft replacement, while offering shorter pump times and lower rates of transfusion and postoperative atrial fibrillation.
Wrapping associated with comparable survival and QoL; should not yet change practice pending randomized trials.
Wrapping and graft replacement are two optional procedures for the treatment of dilated ascending aorta at the time of aortic valve replacement (AVR). Wrapping is considered less invasive. The aim of this study was to compare the short- and long-term clinical outcomes as well as the long-term quality of life in patients undergoing these two procedures.This study enrolled 40 consecutive patients with dilated ascending aorta who had undergone either wrapping (WAA group, n=20) or replacement (RAA group, n=20) of the ascending aorta at the time of AVR. Short-term outcomes, long-term deaths, and aortic events were evaluated, as was quality of life using the SF-36 Short Form. Long-term maximal proximal aortic diameter was also obtained.There were no early deaths in either group. Pump time was shorter, and transfusion (55% vs. 95%, p=0.035) and postoperative atrial fibrillation (5% vs. 30%, p=0.036) rates were lower, in the WAA than in the RAA group. At a mean follow-up of 4.9 years, the overall 5 year survival rates in the WAA and RAA groups were 78.1% and 87.5%, respectively. There were no significant between group differences in SF-36 scores in any subcategory of this survey. Long-term maximal aortic diameter remained stable in both groups. Both surgical interventions for dilated ascending aorta at the time of AVR yield favorable and comparable results in patients with suitable anatomy. Furthermore, we found no differences in quality of life between these procedures.
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Abe et al. (2017) conducted a cohort in Dilated ascending aorta and aortic valve disease (n=40). Wrapping of the ascending aorta vs. Graft replacement of the ascending aorta was evaluated on Overall 5-year survival rate (p=0.50). Wrapping of the ascending aorta during aortic valve replacement resulted in a comparable 5-year survival rate (78.1% vs. 87.5%, p=0.50) and quality of life compared to graft replacement.
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