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January 1, 2019Organic & Biomolecular Chemistry

Recent advances in cobalt-catalysed C–H functionalizations

Alessio Baccalini Stefania Vergura Pravas Dolui Giuseppe Zanoni Debabrata Maiti

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Key Points

The research aims to explore recent developments in the use of cobalt for C–H functionalization processes.
Review of literature on cobalt catalysis in C–H functionalization
Comparison of cobalt with noble metals such as Pd, Rh, and Ir
Analysis of cost, availability, and toxicity of catalysts
Cobalt salts are more readily available and less toxic than noble metals.
Cobalt offers a cost-effective alternative for C–H functionalization.
The research shows increased interest in cobalt-based methodologies.

Implication

Review highlights new cobalt catalysts for C–H functionalization, suggesting a shift from noble metals.

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Cite This Study

Baccalini et al. (2019) studied this question.

synapsesocial.com/papers/6a638f793eb69703d1b7243d https://doi.org/10.1039/c9ob01994d

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1A Brief Review on Recent Developments in C(Sp2)-H and C(Sp3)-H Activation Protocols through Cobalt-catalysis2025
2An Overview of Recent Advances in Cobalt-Catalyzed C-H Functionalization ofUnactivated Aromatic/Aliphatic CompoundsReview · 2026
3The recent advances in cobalt-catalyzed C(sp <sup>3</sup> )–H functionalization reactionsReview · 2022 · 27 citations
4Recent Advances in Cobalt‐Catalyzed Oxidative C‐H Activation2025 · 7 citations
5Cobalt catalyzed open-shell transformationsOriginal Research · 2024

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