Key result
Among critically ill patients with central or extrapontine myelinolysis, 50% had an unfavorable outcome at 1 year, with chronic alcoholism being more frequent in this group (100% vs 72%, P=0.04).
Observational (n=36)
Yes
The prognosis of critically ill patients with central or extrapontine myelinolysis is better than previously thought, with a significant proportion of survivors achieving good functional recovery.
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Challenges prior assumptions of poor prognosis in central myelinolysis; leaves open alcoholism's independent prognostic role.
Louis et al. (2011) conducted an observational in Central or extrapontine myelinolysis (n=36). Central or extrapontine myelinolysis was evaluated on Unfavorable outcome (modified Rankin Scale score >3 or death). Among critically ill patients with central or extrapontine myelinolysis, 50% had an unfavorable outcome at 1 year, with chronic alcoholism being more frequent in this group (100% vs 72%, P=0.04).
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