Atypical Porcine Pestivirus (APPV) was detected in piglets with congenital tremor from two farms in Southern Brazil, showing moderate vacuolization of the cerebellar white matter.
Observational
Yes
This is the first report of APPV in South America, suggesting the virus may be widespread in Brazilian swine herds.
Recently, a putative new pestivirus species, provisionally named as Atypical Porcine Pestivirus (APPV), was associated with the congenital tremor in piglets in North America and consequently in Europe and Asia. The present research aimed to describe the detection and characterization of APPV employing NS5B gene partial sequencing, gross pathology and histologic examination of piglets displaying congenital tremor from two different farms of Southern Brazil. No gross lesions were observed, and the histological findings revealed moderate vacuolization of the white matter of the cerebellum. RT-PCR followed by DNA sequencing and a phylogenetic analysis confirmed the presence of APPV in samples from the two farms, which the samples were distinct in nature. Phylogenetic reconstruction reinforced the high genetic variability within the APPVs previously reported. This is the first report of APPV in South America suggesting that this new group of viruses may be widespread in swine herds in other countries as it is in Brazil.
Mósena et al. (Wed,) conducted a observational in Congenital tremor. Atypical Porcine Pestivirus (APPV) infection was evaluated on Detection and characterization of APPV employing NS5B gene partial sequencing, gross pathology and histologic examination. Atypical Porcine Pestivirus (APPV) was detected in piglets with congenital tremor from two farms in Southern Brazil, showing moderate vacuolization of the cerebellar white matter.