January 1, 2007Annals of Medicine
Novel spectral indexes of heart rate variability as predictors of sudden and non‐sudden cardiac death after an acute myocardial infarction
Key result
The V(index) spectral component of heart rate variability independently predicted sudden cardiac death (RR 4.2; 95% CI 1.2-15.2), while PLF predicted non-sudden cardiac death after an AMI.
Why the study?
Do novel spectral indexes of heart rate variability (V(index) and PLF) predict sudden and non-sudden cardiac death in patients with recent acute myocardial infarction?
Population
590 patients with a recent acute myocardial infarction (AMI)
Design
Cohort
Follow-up
mean 39+/-14 months
Authors
Discussion
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Member takes
Implication
V index and PLF associate with mode-specific cardiac death post-AMI; hypothesis-generating and should not yet change practice.
Study Design
Type
Cohort (n=590)
Structured PICO
Do novel spectral indexes of heart rate variability (V(index) and PLF) predict sudden and non-sudden cardiac death in patients with recent acute myocardial infarction?
P
Population
590 patients with a recent acute myocardial infarction, followed for a mean of 39 months.
E
Exposure
Novel spectral indexes of heart rate variability (V(index) and PLF) analyzed from 24-hour Holter recordings
O
Outcome
Sudden cardiac death (SCD) and non-sudden cardiac deathhard clinical
Main Result
Relative Risk: 4.2 (95% CI 1.2–15.2)
p-value: p=<0.05
Novel spectral HRV indexes V(index) and PLF can independently predict the specific mode of cardiac death (sudden vs. non-sudden) after an acute myocardial infarction.
Cite This Study
Kiviniemi et al. (2007) conducted a cohort in acute myocardial infarction (n=590). V(index) and PLF spectral indexes of heart rate variability was evaluated on Sudden cardiac death (RR 4.2, 95% CI 1.2-15.2, p=<0.05). The V(index) spectral component of heart rate variability independently predicted sudden cardiac death (RR 4.2; 95% CI 1.2-15.2), while PLF predicted non-sudden cardiac death after an AMI.