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April 29, 2005Current Cancer Drug TargetsOpen Access

Modulation of pRb/E2F Functions in the Regulation of Cell Cycle and in Cancer

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Authors

LSLucy SevilleNSNita H. ShahAWAndrew D. Westwell

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Seville et al. (2005) studied this question.

synapsesocial.com/papers/6a63c5611d33332decb35fb3https://doi.org/10.2174/1568009053765816
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Rb/E2F pathway: expanding roles and emerging paradigms2000 · 1,176 citations
  2. 2Role of E2F in cell cycle control and cancer1998 · 226 citations
  3. 3Unusual proliferation arrest and transcriptional control properties of a newly discovered E2F family member, E2F-61998 · 182 citations
  4. 4LIM domains-containing protein 1 (LIMD1), a tumor suppressor encoded at chromosome 3p21.3, binds pRB and represses E2F-driven transcription2004 · 89 citations
  5. 5Target Gene Specificity of E2F and Pocket Protein Family Members in Living Cells2000 · 229 citations