Key result
Patients in a persistent vegetative state exhibited a blood pressure nondipper pattern with significantly higher 24-hour blood pressure and heart rate compared to healthy controls.
Why the study?
Does persistent vegetative state after traumatic brain injury alter circadian blood pressure and heart rate patterns compared to healthy controls?
Population
20 subjects: 10 patients in a persistent vegetative state after traumatic brain injury and 10 healthy…
Comparison
Noninvasive 24-hour ambulatory blood pressure… vs Healthy subjects as controls
Design
Case-control
Follow-up
24 hours
Authors
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Nondipping BP pattern may signal autonomic dysfunction in vegetative states; hypothesis-generating and should not yet change practice.
Case-Control (n=20)
Does persistent vegetative state after traumatic brain injury alter circadian blood pressure and heart rate patterns compared to healthy controls?
Patients in a persistent vegetative state after traumatic brain injury exhibit a nondipper blood pressure pattern with higher overall blood pressure and heart rate and reduced variability, reflecting autonomic dysregulation.
Pattoneri et al. (2005) conducted a case-control in Persistent vegetative state after traumatic brain injury (n=20). Persistent vegetative state vs. Healthy subjects was evaluated on Circadian blood pressure and heart rate pattern and variability. Patients in a persistent vegetative state exhibited a blood pressure nondipper pattern with significantly higher 24-hour blood pressure and heart rate compared to healthy controls.
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