Why the study?
Inspiratory muscle training reduces blood pressure in hypertensive patients, but no synthesis of its effectiveness in normotensive individuals existed.
Population
134 normotensive adults across six studies, mostly young men aged 20–27 years
Comparison
Isolated inspiratory muscle training at varying loads (75% vs <= 40% maximum inspiratory pressure)
Design
Systematic review of randomized clinical trials and intervention studies
Follow-up
Six-week protocols and acute sessions
Answers are grounded in this paper and cite their sources.
Supports high-intensity inspiratory muscle training for primary BP prevention in normotensives; extends benefits seen in hypertensives to lower-risk adults.
Systemic arterial hypertension is a predominant risk factor for cardiovascular diseases, thus small reductions in blood pressure (BP) can slow progression and cardiovascular risk. Inspiratory muscle training (IMT) is a portable and low‐cost intervention with effects that reduce BP in hypertensive patients, but there was no synthesis of its effectiveness in normotensive patients. This systematic review, registered in PROSPERO (CRD420251112144) and conducted according to PRISMA, searched for randomized clinical trials/intervention studies up to June 2026 in PubMed, PEDro, Virtual Health Library, Web of Science, Scopus, and gray literature. Normotensive adults undergoing isolated IMT were included, with outcomes of systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), or heart rate (HR); two reviewers selected studies, extracted data, and assessed risk of bias (RoB 2 and ROBINS‐I). Among 2,564 records, six studies (134 participants) were eligible; volunteers were mostly young men (20–27 years) with baseline BP ∼115/75 mmHg. Six‐week protocols with 75% of maximum inspiratory pressure (MIP) and 30 breaths per day reduced SBP by 4.3–9.6 mmHg and DBP by 3.9–6.1 mmHg without altering cardiac output; loads ≤ 40% MIP did not modify BP. Acute sessions demonstrated transient increases in BP and HR during exercise followed by sympathetic suppression during recovery. It is concluded that high‐intensity IMT can reduce BP in normotensive individuals and be a non‐pharmacological strategy for primary prevention, but current evidence is limited and heterogeneous. Larger randomized trials with standardized protocols and ambulatory monitoring are needed to confirm the benefits.
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Barbosa et al. (2026) studied this question.
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