Key result
An aortic diameter greater than 50 mm after aortic valve replacement was associated with a 27% incidence of acute aortic dissection, compared to an overall incidence of 0.6%.
Why the study?
Does aortic dilatation > 50 mm increase the risk of acute aortic dissection in patients who have undergone aortic valve replacement?
Cohort (n=419)
Does aortic dilatation > 50 mm increase the risk of acute aortic dissection in patients who have undergone aortic valve replacement?
An aortic diameter exceeding 50 mm after aortic valve replacement is associated with a 27% incidence of acute aortic dissection, indicating a need for prophylactic valved conduit implantation or early elective reoperation.
Answers are grounded in this paper and cite their sources.
Aortic diameter ≥50 mm at AVR may flag later dissection risk; leaves open optimal size thresholds for concomitant aortic surgery.
From 1986 to 1994, 10 patients were observed to have developed an acute aortic dissection at some stage after an aortic valve replacement (AVR). Study of the characteristics of these patients showed that all patients had an aortic diameter of 50 mm or more (range 50 to 80 mm, mean 64 mm), and 70% suffered from systemic hypertension. Subsequently, the echocardiographic database, containing data from 33,105 studies in 21,484 patients, was searched for cases of AVR in which an accurate aortic dimension could be measured. Of 524 patients who had undergone AVR, an accurate aortic diameter was recorded in 419. Thirty-seven patients had an aortic size greater than 50 mm. All acute dissections occurred in this group of patients. The incidence of acute dissections among patients with significant aortic dilatation following AVR was 27%, whereas the overall incidence of acute dissection after AVR is 0.6%. Although there was a preponderance of tilting disc mechanical valves in the dissecting patients, the type of valve implanted does not seem to be of any importance. From these observations, we conclude that implantation of a valved conduit is indicated even in the presence of mild annuloaortic ectasia (aortic size = 50 mm). Patients who have had an AVR and show an enlarging aortic diameter exceeding 50 mm should have an elective reoperation at an early stage, especially when systemic hypertension is present.
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Prenger et al. (1994) conducted a cohort in Aortic valve replacement (n=419). Aortic size > 50 mm vs. Overall AVR patients was evaluated on Acute aortic dissection. An aortic diameter greater than 50 mm after aortic valve replacement was associated with a 27% incidence of acute aortic dissection, compared to an overall incidence of 0.6%.
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