Key result
A 15-year-old girl with acute disseminated encephalomyelitis responded well to a 5-day regimen of high-dose methylprednisolone, with neurologic deficits improving by the third day of hospitalization.
Case Report (n=1)
No
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High-dose corticosteroids were effective in treating a 15-year-old girl with acute disseminated encephalomyelitis (ADEM), highlighting the need to consider this rare diagnosis in emergency settings.
Introduction: Acute disseminated encephalomyelitis (ADEM) is an uncommon monophasic idiopathic inflammatory demyelinating disease. ADEM typically presents with non-specific symptoms including nausea, vomiting, fever, and headache. This then progresses to neurological deficits such as motor weakness, altered sensorium, and often significant morbidity or mortality. Typically, the infectious insult is thought to be in transient viral infection or vaccination. Case Report: We describe a case of ADEM in a 15-year-old girl that came to emergency department with dizziness and general weakness; she was unable to speak, and lethargic, with no positive past history. Her laboratory tests and spiral brain computed tomography (CT) scan were normal. She was admitted to neurology ward, and threated with high-dose corticosteroids. Our patient responded well to corticosteroids. Conclusion: In patients with neurologic deficits in emergency department, the physician must think about ADEM although it is rare.
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Nemati-Ahmadabad et al. (2019) conducted a case report in Acute disseminated encephalomyelitis (ADEM) (n=1). High-dose methylprednisolone was evaluated on Neurologic deficit improvement. A 15-year-old girl with acute disseminated encephalomyelitis responded well to a 5-day regimen of high-dose methylprednisolone, with neurologic deficits improving by the third day of hospitalization.
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