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November 30, 2015Expert Review of Neurotherapeutics

Diagnosis and therapy of acute disseminated encephalomyelitis and its variants

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Population

Patients with acute disseminated encephalomyelitis (ADEM) and its variants

Design

Review

Authors

GBGiulia BerzeroVita-Salute San Raffaele UniversityACAndrea CorteseUniversity of PaviaSRSabrina RavagliaUrology Foundation

Discussion

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Implication

Provides synthesis of ADEM management for clinicians; leaves open prospective validation of outcome predictors.

Structured PICO

P
Population
Patients with acute disseminated encephalomyelitis (ADEM) and its variants

This paper reviews the clinical profile, potential predictors of outcome, and current treatment strategies for acute disseminated encephalomyelitis (ADEM).

Limitations

  • Literature on the matter is scarce, mostly consisting of retrospective studies

Cite This Study

Berzero et al. (2015) studied this question.

synapsesocial.com/papers/6a7f5d27facb7ef7378b17c6https://doi.org/10.1586/14737175.2015.1126510
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Acute Disseminated Encephalomyelitis in Children2002 · 353 citations
  2. 2Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis2013 · 1,471 citations
  3. 3Relapsing demyelinating disease affecting both the central and peripheral nervous systems2008 · 60 citations
  4. 4Leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation: clinical and genetic characterization and target for therapy2014 · 110 citations
  5. 5Acute Disseminated Encephalomyelitis2005 · 368 citations