Key result
Pediatric acute disseminated encephalomyelitis shows universal survival but leaves ~17% with long-term neurologic sequelae.
Why the study?
Epidemiologic, clinical, neuroimaging, laboratory features, treatment, and outcomes of children with acute disseminated encephalomyelitis were not well described.
Design
6-year retrospective chart review
Authors
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Case series supports good survival in pediatric ADEM; leaves open confirmation of seasonal respiratory triggers and sequelae rates.
Observational (n=18)
ADEM in children is likely associated with winter/spring respiratory viruses, has characteristic MRI findings, and generally carries an excellent prognosis for survival.
Murthy et al. (2002) conducted an observational in Acute disseminated encephalomyelitis (n=18). Acute disseminated encephalomyelitis was evaluated on Long-term neurologic sequelae. Among 18 children with acute disseminated encephalomyelitis, all patients survived and 17% experienced long-term neurologic sequelae.
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