Key result
Intensive glucose control did not reduce cardiovascular events in long-duration type 2 diabetes, though early intensive therapy in UKPDS showed a 15% reduction in myocardial infarction risk.
Why the study?
Does intensive glucose control reduce cardiovascular complications in patients with type 2 diabetes?
Population
Patients with type 2 diabetes
Comparison
Intensive glucose control / intensive therapy vs Conventional therapy
Design
Editorial
Authors
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While early intensive glucose control may offer a legacy effect in reducing MI risk, intensive therapy in long-standing type 2 diabetes does not appear to reduce CVD events and may increase mortality.
Does intensive glucose control reduce cardiovascular complications in patients with type 2 diabetes?
While early intensive glucose control may offer a legacy effect in reducing MI risk, intensive therapy in long-standing type 2 diabetes does not appear to reduce CVD events and may increase mortality.
Vinik et al. (2010) conducted an editorial in Type 2 diabetes. Intensive glucose control vs. Conventional therapy was evaluated. Intensive glucose control did not reduce cardiovascular events in long-duration type 2 diabetes, though early intensive therapy in UKPDS showed a 15% reduction in myocardial infarction risk.
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