Key result
Maternal diabetes was associated with a significantly higher fetal modified myocardial performance index compared to controls (0.43 vs 0.37, P<0.0001).
Why the study?
Does maternal diabetes affect fetal cardiac function as measured by the modified myocardial performance index (Mod-MPI)?
Population
Fetuses of pregnant patients with diabetes between 30 and 40 weeks of gestation, and healthy controls.
Comparison
Maternal diabetes (gestational or pregestational) vs Controls (fetuses of non-diabetic mothers)
Design
Cross-sectional
Authors
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May flag subclinical fetal cardiac dysfunction in diabetes; leaves open whether Mod-MPI predicts outcomes or alters management.
Observational
Does maternal diabetes affect fetal cardiac function as measured by the modified myocardial performance index (Mod-MPI)?
Absolute Event Rate: 0.43% vs 0.37%
p-value: p=<0.0001
Fetal modified myocardial performance index is elevated in pregnancies complicated by diabetes, particularly in those with worse maternal disease and large fetal size.
Figueroa et al. (2012) conducted an observational in Pregnancies complicated by diabetes. Maternal diabetes vs. Controls was evaluated on Modified myocardial performance index (Mod-MPI) (p=<0.0001). Maternal diabetes was associated with a significantly higher fetal modified myocardial performance index compared to controls (0.43 vs 0.37, P<0.0001).
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