Key result
Stentless bioprostheses for RVOT replacement after the Ross procedure had a higher incidence of reintervention compared to homografts (1 in 36 vs 1 in 150 patient years; P=0.007).
Why the study?
Does RVOT replacement with stentless bioprostheses compared to homografts increase the risk of reintervention in adult patients undergoing the Ross procedure?
Population
186 adult patients undergoing aortic root replacement with a pulmonary autograft
Comparison
Right ventricular outflow tract replacement with… vs Right ventricular outflow tract replacement with…
Design
Cohort
Follow-up
mean 6 years (range 1-15 years)
Authors
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Bioprosthetics may serve as alternative to homografts for adult Ross RVOT reconstruction; leaves open need for randomized durability data.
Cohort (n=186)
Does RVOT replacement with stentless bioprostheses compared to homografts increase the risk of reintervention in adult patients undergoing the Ross procedure?
p-value: p=0.007
In adult patients undergoing the Ross procedure, RVOT replacement with stentless bioprostheses is associated with a significantly higher risk of reintervention and higher gradients compared to homografts.
Miskovic et al. (2012) conducted a cohort in Right ventricular outflow tract replacement in Ross procedures (n=186). Stentless bioprostheses (Medtronic Freestyle) vs. Homograft was evaluated on Incidence of reintervention owing to dysfunction of the RVOT replacement (p=0.007). Stentless bioprostheses for RVOT replacement after the Ross procedure had a higher incidence of reintervention compared to homografts (1 in 36 vs 1 in 150 patient years; P=0.007).
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